Lihong ZHANG （张丽红)
	Associate Professor B.Med., M.Med., MD & Ph.D.
	Department of Anatomy, Histology & Embryology 138 Yixueyuan Road Shanghai, 200032 China
	Phone: + 86 (21) 54237019, Ext. 9208 Fax: + 86 (21) 54237027 Office: Room 208, 9 Building (east)
	E-mail: zhanglh@fudan.edu.cn

 

Background

  

Education/Training

·             B.Med., Dalian Medical University, Dalian, China (1992-1997)

·             M.Med., Liaoning University of TCM, Shenyang, China (2002-2005)

·             M.D. & Ph.D., China Medical University, Shenyang, China (2005-2008)

·             Visiting Scholar, University of New South Wales, Sydney, Australia (2013-2014)

 

 

Other Affiliations

·             Member, Chinese Society for Anatomical Sciences

·             Member, Shanghai Society for Anatomy Science

·             Member, Shanghai Medical Asssociation

 

 

 

Teaching

Courses

·             Histology & Embryology

·             Histology & Embryology (English)

·             Developmental Neurobiology

·             Histological Progress

·             Embryological Progress

Awards and Honors

·             2012, The Second Award in National Medical College Teaching Contest.

·             2009, The Second Award in English Teaching Contest of Shanghai Medical College.

·             2007, Excellent Young Teacher of Liaoning University of TCM.

·             2007, The First Award in Multimedia Courseware Making competition of Liaoning University of TCM.

·             2004, The Second Award in Bilingual Teaching Contest of Liaoning University of TCM.

 

Research

 

 

Research Interests

·             Trace element zinc and its related protein

·             Neurodegenerative diseases

·             Neuroblastoma

 

 

 

Research Description

An increasing amount of evidence shows the linkage between trace elements homeostasis and human disease, including neurodegenerative diseases and neuroblastoma. Zinc, an essential trace element for mammals, is abundant in the nervous system and has been suggested to be involved in many biological functions. Zinc cannot travel across biological membranes by passive diffusion. In mammals, two zinc transporter families (ZIP, SLC39 and ZnT, SLC30) are required for transporting zinc across the plasma membrane and distributing zinc around the cell. Our finding of zinc-enriched senile plaques in Alzheimers’ (a disease of progressive intellectual deterioration) brain indicates the important roles of zinc and its related protein in the pathologic process of nervous system diseases.

 

 

Research Grants

·             2012.01~2014.12: National Nature Science Foundation of China (NSFC).

·             2012.01~2014.12: Specialized Research Fund for the Doctoral Program of Higher Education of China.

·             2008.12~2010.11: Youth Scientific Foundation of Shanghai Medical College.

·             2006.01~2007.12: Youth Scientific Foundation of Education Office of Liaoning Province.

 

Selected Publications 

 

1.    Zhang L, Sokolowski N, Atmadibrata B and Liu T. (2014). Histone demethylase JARID1B promotes cell proliferation but is downregulated by N-Myc oncoprotein. Oncology Report, 31(4):1935-1939.

2.    Atmadibrata B, Liu PY, Sokolowski N, Zhang L, Wong M, Tee AE, Marshall GM and Liu T. (2014). The novel long noncoding RNA linc00467 promotes cell survival but is down-regulated by N-Myc. PLoS One, 9(2):e88112.

3.    Zhang L., Wang X., Zheng Z., Ren H., Stoltenberg M., Danscher G., Huang L., Rong M. and Wang Z. (2010). Altered expression and distribution of zinc transporters in APP/PS1 transgenic mouse brain. Neurobiology of Aging, 31(1):74-87.

 

4.    Zhang L, Wang X, Stoltenberg M, Danscher G, Huang L and Wang Z. (2008). Abundant expression of zinc transporters in the amyloid plaques of Alzheimer’s disease brain, Brain Research Bulletin, 77(5):55-60.