丁晓明(Xiaoming Ding)

E-mail: xmding74@fudan.edu.cn

1992-1996就读于武汉大学生命科学学院，获学士学位。1996-2002于中国科学院上海生命科学院植物生理生态所，获博士学位。2002-2003于诺丁汉大学女王医学中心遗传研究所、2003-2005于阿伯丁大学医学科学研究所从事博士后工作。2005.6-至今，复旦大学生命科学学院微生物系，讲师，副教授。

Undergraduate studies at the School of Life Sciences, Wuhan University (1996-2002); Ph.D. in Institute of Plant Physiology and Ecology, Shanghai Institute of Biological Sciences, Chinese Academy of Sciences; Postdoctoral fellow at the Institute of Genetics, Queen's Medical Center, University of Nottingham (2002-2005) and the Institute of Medical Sciences, University of Aberdeen (2003-2005); 2005.6-present, Lecturer, Associate Professor, Department of Microbiology, School of Life Sciences, Fudan University.

主要研究方向（Research Interests)

合成生物学，微生物分子遗传学及代谢调控

Synthetic biology, Microbial molecular genetics, Regulation of microbial metabolism

近年代表性成果（*为通讯作者）：

1.Lei X, Wang L, Zhao G, Ding X*. (2018) Site-specificity of serine integrase demonstrated by the attB sequence preference of ϕBT1 integrase. FEBS Lett. 592(8):1389-1399

2.Yu Y, Tang B, Dai R, Zhang B, Chen L, Yang H, Zhao G*, Ding X*. (2018) Identification of the streptothricin and tunicamycin biosynthetic gene clusters by genome mining in Streptomyces sp. strain fd1-xmd. Appl Microbiol Biotechnol. 102(6):2621-2633.

3.Wang H, Zhao G*, Ding X*.(2017) Morphology engineering of Streptomyces coelicolor M145 by sub-inhibitory concentrations of antibiotics. Scientific Reports. 7(1): 13226.

4.Bian X, Tang B, Yu Y, Tu Q, Gross F, Wang H, Li A, Fu J, Shen Y, Li YZ, Stewart AF, Zhao G, Ding X*, Müller R*, Zhang Y*. (2017) Heterologous production and yields improvement of epothilones in the Burkholderiales strain DSM 7029. ACS chemical biology. 12(7) (2017):1805-1812.

5.Li C, Liu X, Lei C, Yan H, Shao Z, Wang Y, Zhao G, Wang J*, Ding X.*. (2017). RifZ (AMED_0655) Is a Pathway-Specific Regulator for Rifamycin Biosynthesis in Amycolatopsis mediterranei. Appl Environ Microbiol. 83(8). pii: e03201-16.